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Anticancer research · Sep 2013
Review Case ReportsPancreatic neuroendocrine tumor with ectopic adrenocorticotropin production: a case report and review of literature.
- Forum B Patel, Simon Khagi, Kevin P Daly, Ronald M Lechan, Vorawan Ummaritchot, and Muhammad W Saif.
- Department of Medicine and Cancer Center, Tufts Medical Center, 800 Washington Street Box 245, Boston, MA 02111, U.S.A. wsaif@tuftsmedicalcenter.org.
- Anticancer Res. 2013 Sep 1; 33 (9): 4001-5.
AbstractPancreatic neuroendocrine tumors (p-NETs) entail a vast array of tumors, which can vary from benign neoplastic growths to rapidly aggressive malignancies. Such is the case with ectopic adrenocorticotropic hormone (ACTH)-producing p-NETs. These tumors have been found to be quite aggressive and a challenge to treat, especially due to the occurrence of metastatic disease even after resection of the primary tumor. We discuss the case of a 44-year-old female who initially presented with vague, non-specific symptoms, in which a malignant p-NET was found to be the cause of her clinical presentation. Although resection of the pancreatic mass was performed, the patient presented again with metastatic disease to the liver.
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