• Am. J. Respir. Crit. Care Med. · Nov 2021

    Dynamic Metabolic Risk Profiling of World Trade Center-Lung Disease: A Longitudinal Cohort Study.

    • Sophia Kwon, Myeonggyun Lee, George Crowley, Theresa Schwartz, Rachel Zeig-Owens, David J Prezant, Mengling Liu, and Anna Nolan.
    • Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine.
    • Am. J. Respir. Crit. Care Med. 2021 Nov 1; 204 (9): 1035-1047.

    AbstractRationale: Metabolic syndrome (MetSyn) increases the risk of World Trade Center (WTC) lung injury (LI). However, the temporal relationship of MetSyn, exposure intensity, and lung dysfunction is not well understood. Objective: To model the association of longitudinal MetSyn characteristics with WTC lung disease to define modifiable risk. Methods: Firefighters, for whom consent was obtained (N = 5,738), were active duty on September 11, 2001 (9/11). WTC-LI (n = 1,475; FEV1% predicted

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