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Review Comparative Study
New fibrinolytic agents for MI: as effective as current agents, but easier to administer.
- Keith Ellis and Sorin Brener.
- Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, OH 44195, USA.
- Cleve Clin J Med. 2004 Jan 1; 71 (1): 20, 23-5, 29-30 passim.
AbstractThe efficacy and safety of fibrinolytic agents have not dramatically changed since alteplase (Activase), a derivative of tissue plasminogen activator (t-PA), was introduced nearly 2 decades ago. However, newer agents have a longer half-life, making them easier to deliver. Fibrinolytic therapy is underused in many patients, especially in those traditionally thought to be at high risk for complications.
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