• NawsherwanDepartment of Preventive Medicine, School of Health Sciences, Wuhan University, Wuhan, Hubei, China., Abbas Khan, Sumaira Mubarik, Ghulam Nabi, Cuifang Fan, and Suqing Wang.
• Department of Preventive Medicine, School of Health Sciences, Wuhan University, Wuhan, Hubei, China.
• J Res Med Sci. 2021 Jan 1; 26: 38.

BackgroundPreeclampsia (PE) and premature rupture of membrane (PROM) are considered significant risk factors for lower neonatal birth weight and birth length. However, very limited studies have reported the impact of PE and PROM on neonatal birth weight and birth length by gestational week. Therefore, we aimed to determine the effect of PE and PROM on neonatal birth weight and length by gestational age.Materials And MethodsA total of 9707 singleton neonates were selected for this study. All the data were collected and documented in the obstetric register by the trained nurses in the Gynecology and Obstetrics Department.ResultsThe neonatal mean birth weights and birth lengths were statistically significantly (P < 0.05) lowered among preeclamptic mothers compared to mothers without PE throughout the gestational age. Statistically significantly (P < 0.05) lowered mean birth weights and birth lengths were found among neonates born to mothers with PROM than among neonates born to mothers without PROM by all gestational weeks except for 32 weeks and 36 weeks. Moreover, in a multiple linear regression model, PE and PROM were significantly negatively associated with neonatal birth weights and birth lengths by almost all gestational weeks (β <0, P < 0.05).ConclusionWe concluded that after adjustment for covariates and confounding factors, PE and PROM had a significantly negative association with neonatal birth weights and birth lengths by all gestational weeks.Copyright: © 2021 Journal of Research in Medical Sciences.

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