• Cleve Clin J Med · Jun 1990

    Review

    Evaluation of wheezing in the nonasthmatic patient.

    • D A Holden and A C Mehta.
    • Department of Pulmonary Medicine, Cleveland Clinic Foundation, One Clinic Center, Ohio 44195.
    • Cleve Clin J Med. 1990 Jun 1; 57 (4): 345-52.

    AbstractWheezing is a nonspecific manifestation of airway obstruction. Even though bronchial asthma is the most common cause of wheezing, a variety of pulmonary and nonpulmonary conditions can present with this symptom. In recent years methacholine provocation challenge has simplified detection of bronchial asthma; however, establishing accurate diagnosis of other causes of wheezing is important because each condition requires specific treatment. This article describes a methodical approach to the diagnosis of wheezing in patients who are not asthmatic.

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