• Wiad. Lek. · Jan 2015

    Review

    [Acute kidney injury after hematopoietic cell transplantation].

    • Mariusz Mieczkowski and Paweł Kulicki.
    • Katedra i Klinika Nefrologii, Dializoterapii i Chorób Wewnętrznych, Warszawski Uniwersytet Medyczny, Warszawa.
    • Wiad. Lek. 2015 Jan 1; 68 (4 Pt 2): 678-9.

    AbstractStem cell transplantation is now a routine and successful therapeutic method in many hematopoietic disorders and cancers. Unfortunately, toxicity of the procedure significantly worsens the outcomes, with acute and chronic kidney injury among the others. Etiology of kidney failure is multifactorial with nephrotoxicity of drugs, septic complications, sinusoidal occlusion syndrome, thrombotic microangiopathy and acute/chronic graft-versus-host disease (GvHD). Understanding these syndromes enables early recognition and proper intervention that can reduce incidence and severity of kidney injury and improve outcomes.

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