• Anesthesia and analgesia · Dec 1985

    Randomized Controlled Trial Clinical Trial

    Does intravenous lidocaine prevent laryngospasm after extubation in children?

    • P Leicht, T Wisborg, and B Chraemmer-Jørgensen.
    • Anesth. Analg. 1985 Dec 1;64(12):1193-6.

    AbstractOne hundred otherwise healthy children undergoing tonsillectomy were investigated in a double-blind study to examine the effect of intravenous lidocaine in preventing laryngospasm upon extubation. The children were anesthetized with N2O-O2-halothane and orally intubated. They were randomly given lidocaine, 1.5 mg/kg, or saline intravenously prior to extubation, which took place at the same depth of anesthesia, namely when there were signs of swallowing activity. Eleven children (2%) in each group of 50 developed laryngospasm. From our findings it is concluded that lidocaine, 1.5 mg/kg, does not prevent laryngospasm upon extubation when extubation is carried out at the start of swallowing activity.

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