• Mislav Vrsalović and Vrsalović PresečkiAnaA1University of Zagreb, School of Medicine, Zagreb, Croatia; 2Department of Cardiology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 3Faculty of Chemical Engineering and Technology, University of Zagreb, Zagreb, Cro.
• 1University of Zagreb, School of Medicine, Zagreb, Croatia; 2Department of Cardiology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 3Faculty of Chemical Engineering and Technology, University of Zagreb, Zagreb, Croatia.
• Acta Clin Croat. 2021 Mar 1; 60 (1): 115-119.

AbstractAcute aortic dissection (AAD) is a serious medical emergency that requires early diagnosis and rapid treatment. Whether cardiac troponin could be an independent prognostic marker in patients with type A AAD is still unknown. We systematically searched Medline and Scopus to identify all observational cohort studies published before January 2020 that compared outcome (in-hospital mortality) in patients with type A AAD with and without troponin elevation on admission. Four studies with 412 patients were included in final analysis (median age 59 years, 65% of males). A total of 124 (30%) patients died during in-hospital stay, and 73% underwent surgery. Elevated troponins (39.6% of patients) were associated with an increased risk of short-term mortality (adjusted odds ratio 1.26; 95% confidence interval 1.08-1.47), with low heterogeneity among studies (I2 =29.81%). Elevated troponins on admission are independently associated with increased in-hospital mortality in type A AAD.

15 keywords...

hide…