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- Benita Tjoe, Lili Barsky, Janet Wei, Bruce Samuels, Babak Azarbal, MerzC Noel BaireyCNBDirector, Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA; Investigator, Women's Ischemia Trial to Reduce Events in Nonobstructive CAD (WARRIOR) NCT03417388; Investigator, Wome, and Chrisandra Shufelt.
- Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA.
- Cleve Clin J Med. 2021 Oct 1; 88 (10): 561571561-571.
AbstractIschemia and no obstructive coronary artery disease (INOCA) is an increasingly recognized cause of angina, and it is more commonly diagnosed in women. Coronary microvascular dysfunction (CMD), or the abnormal dilation and constriction of the small vessels of the heart, is the underlying cause of INOCA in one-half of cases. This review discusses coronary microvascular pathophysiology, considerations for invasive coronary function testing and noninvasive diagnostic modalities, implications for management, and remaining knowledge gaps.Copyright © 2021 The Cleveland Clinic Foundation. All Rights Reserved.
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