• Saudi Med J · Oct 2021

    Clinical and epidemiological characteristics of COVID-19 mortality in Saudi Arabia.

    • Rawabi M Alsayer, Hassan M Alsharif, Abeer M Al Baadani, and Kiran A Kalam.
    • From the Scientific Research Center (Alsayer); from the Department of Infectious Disease (Al Baadani, Kalam), Prince Sultan Military Medical City, Riyadh, and from the Department of Intensive Care (Alsharif), King Fahad Armed Forces Hospital, Jeddah, Kingdom of Saudi Arabia.
    • Saudi Med J. 2021 Oct 1; 42 (10): 108310941083-1094.

    ObjectivesTo analyze the clinical and epidemiological characteristics for 224 of in-hospital coronavirus disease 2019 (COVID-19) mortality cases. This study's clinical implications provide insight into the significant death indicators among COVID-19 patients and the outbreak burden on the healthcare system in the Kingdom of Saudi Arabia (KSA).MethodsA multi-center retrospective cross-sectional study conducted among all COVID-19 mortality cases admitted to 15 Armed Forces hospitals across KSA, from March to July 2020. Demographic data, clinical presentations, laboratory investigations, and complications of COVID-19 mortality cases were collected and analyzed.ResultsThe mean age was 69.66±14.68 years, and 142 (63.4%) of the cases were male. Overall, 30% of the COVID-19 mortalities occurred in the first 24 hours of hospital admission, while 50% occurred on day 10. The most prevalent comorbidities were diabetes mellitus (DM, 73.7%), followed by hypertension (HTN, 69.6%). Logistic regression for risk factors in all mortality cases revealed that direct mortality cases from COVID-19 were more likely to develop acute respiratory distress syndrome (odds ratio [OR]: 1.75, confidence intervel [CI: 0.89-3.43]; p=0.102) and acute kidney injury (OR: 1.01, CI: [0.54-1.90]; p=0.960).ConclusionAging, male gender and the high prevalence of the underlying diseases such as, DM and HTN were a significant death indicators among COVID-19 mortality cases in KSA. Increases in serum ferritin, procalcitonin, C-reactive protein (CRP), and D-dimer levels can be used as indicators of disease progression.Copyright: © Saudi Medical Journal.

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