• Zh Nevrol Psikhiatr · Jan 2021

    [Clinical features of temporal lobe epilepsy with involvement of the insular lobe].

    • R G Khachatryan, T M Alekseeva, W A Khachatryan, K I Sebelev, and N P Alekseeva.
    • Almazov National Medical Research Center, St. Petersburg, Russia.
    • Zh Nevrol Psikhiatr. 2021 Jan 1; 121 (6): 7-12.

    ObjectiveTo determine the clinical features of the course of the disease when the insular lobe is involved in the epileptic process.Material And MethodsA comparative analysis of the results of diagnosis and treatment of 55 patients with temporal lobe epilepsy and 46 patients with temporal plus epilepsy was carried out. The results of neuroimaging, clinical and EEG studies were compared.ResultsAutonomic paroxysms of nausea and hypersalivation, skin changes, simple motor seizures, emotional seizure and sensory paroxysms are the most reliable signs of the involvement of the insular lobe in the epileptic process in temporal plus epilepsy. For 'pure' temporal lobe epilepsy, cognitive paroxysms of the déjà vu and aura are common. When the insular lobe is involved in the epileptic process, the seizures have a reliably high frequency, polymorphism and are more complex by structure.ConclusionParoxysmal syndrome in temporal plus epilepsy with involvement of the insular lobe undergoes significant changes in the form of increased seizures and the appearance of specific seizures and characteristic polymorphism.

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