• Dae Yong Kim, Dae Young Hong, Sin Young Kim, Jeong Jin Park, KimJong WonJWDepartment of Emergency Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea., Sang O Park, Kyeong Ryong Lee, and Kwang Je Baek.
• Department of Emergency Medicine, Konkuk University Medical Center, Seoul, Republic of Korea.
• Medicine (Baltimore). 2021 Sep 17; 100 (37): e27255.

AbstractThis study was performed to determine whether red blood cell distribution width (RDW) is associated with 3-month poor functional outcome in patients undergoing thrombolytic therapy for acute ischemic stroke.RDW was measured in patients with thrombolytic therapy in emergency department. Functional outcome was assessed after 3 months and poor functional outcome was defined as modified Rankin scale 3 to 6.A total of 240 patients were enrolled, and 82 (34.2%) had a poor functional outcome. The median RDW was significantly elevated in patients with a poor functional outcome compare with those with a good outcome. RDW was independently associated with a 3-month poor functional outcome (odds ratio 3.369, 95% confidence interval 2.214-5.125). The optimal RDW cutoff for predicting 3-month poor functional outcome was 12.8%, and the area under the curve for RDW was 0.818 (95% confidence interval 0.761-0.876). The area under the curve for RDW was higher in male patients than in female patients. The RDW correlated positively with the modified Rankin scale score after 3 months and the initial National Institutes of Health Stroke Scale score.Initial higher RDW level is related to a 3-month poor functional outcome in patients undergoing thrombolytic therapy for acute ischemic stroke.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

42 keywords...

hide…