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Asian Cardiovasc Thorac Ann · Jun 2002
Thymoma associated with pure red-cell aplasia: clinical features and prognosis.
- Tomohiro Murakawa, Jun Nakajima, Hajime Sato, Makoto Tanaka, Shinichi Takamoto, and Masashi Fukayama.
- Department of Cardiothoracic Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan. murakawa-tky@umin.ac.jp
- Asian Cardiovasc Thorac Ann. 2002 Jun 1; 10 (2): 150-4.
AbstractAs information on the clinical features and prognosis of thymoma complicated by pure red-cell aplasia is limited, follow-up data on thymoma patients who had a thymectomy between 1954 and 1999 were analyzed retrospectively. Six of 166 cases were complicated by pure red-cell aplasia. In 3 of these, the pure red-cell aplasia appeared after surgical intervention. Remission was observed in 2 patients who underwent extended thymectomy. The other 4 patients subsequently died from pure red-cell aplasia. The outcome in patients with pure red-cell aplasia was poorer than that in the entire group of patients with thymoma and in those with thymoma complicated by myasthenia gravis. The possible onset of pure red-cell aplasia after thymectomy should be kept in mind during follow-up.
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