• Janett A Hildebrand, John Billimek, Jung-Ah Lee, Dara H Sorkin, Ellen F Olshansky, Stephen L Clancy, and Lorraine S Evangelista.
• University of Southern California, Suzanne Dworak-Peck School of Social Work, Department of Nursing. Electronic address: jhildebr@uci.edu.
• Patient Educ Couns. 2020 Feb 1; 103 (2): 266-275.

PurposeThis systematic review and meta-analysis evaluated the effectiveness of diabetes self-management education (DSME) in reducing glycosylated hemoglobin (A1C) levels in adult Latinos with type 2 diabetes (T2DM).MethodsFive databases were searched for DSME randomized controlled trials or quasi-experimental trials published between January 1997 and March 2019. A random effects model was utilized to calculate combined effect sizes. Subgroup analyses were performed to explore possible sources of heterogeneity between studies.ResultsTwenty-three unique studies met criteria for this systematic review and of these, 18 were included in the meta-analysis. Pooled estimate effect of DSME on A1C from the random effect model was -0.240 (95% confidence interval = -0.345, -0.135, p <  0.001). There was moderate heterogeneity (Cochrane Q=30.977, P=0.020, I^2 = 45.121) between the studies. Subgroup analyses demonstrated greater A1C reductions in studies with intervention duration ≤6 months, initial A1C baseline values >8.0 [69 mmol/mol], and team-based approach.ConclusionsMeta-analysis results showed that culturally tailored DSME interventions significantly reduce AIC in Latinos with T2DM despite the heterogeneity across the studies.ImplicationsThe heterogeneity in the study methodologies reinforce the need for additional studies to better understand DSME interventions to reduce disparities in Latino adults with T2DM.Copyright © 2019 Elsevier B.V. All rights reserved.

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