• Anna C Alegiani, Franziska Dorn, Moriz Herzberg, Frank A Wollenweber, Lars Kellert, Eberhard Siebert, Christian H Nolte, Regina von Rennenberg, Elke Hattingen, Gabor C Petzold, Felix J Bode, Waltraud Pfeilschifter, Jan H Schäfer, Marlies Wagner, Joachim Röther, Bernd Eckert, Peter Kraft, Mirko Pham, Tobias Boeckh-Behrens, Silke Wunderlich, Kathleen Bernkopf, Arno Reich, Martin Wiesmann, Anastasios Mpotsaris, Marios Psychogios, Jan Liman, Ilko Maier, Jörg Berrouschot, Albrecht Bormann, Volker Limmroth, Joachim Spreer, Martina Petersen, Lars Krause, Stephan Lowens, Christoffer Kraemer, Sarah Zweynert, Kristin S Lange, Sven Thonke, Andreas Kastrup, Panagiotis Papanagiotou, Burkhard Alber, Michael Braun, Jens Fiehler, Christian Gerloff, Martin Dichgans, and Götz Thomalla.
• 1 Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
• Int J Stroke. 2019 Jun 1; 14 (4): 372-380.

BackgroundEndovascular treatment has become standard of care for the treatment of acute ischemic stroke with large vessel occlusion. However, patients treated in clinical practice differ from the selected populations randomized in clinical trials.AimsThe German Stroke Registry Endovascular Treatment (GSR-ET) aims at a systematic evaluation of outcome, safety, and process parameters of endovascular stroke treatment in standard of care in Germany.MethodsThe GSR-ET is an academic, independent, prospective, multicenter, observational registry study. Participating stroke centers from all over of Germany consecutively enroll patients transferred to the angiography suite with an intention to be treated with endovascular stroke treatment. Patients receive regular care. Data are collected as part of clinical routine. Baseline clinical and procedural information and clinical follow-up information after 90 days are recorded. Here, we present an analysis of baseline data of the first 1662 patients included in the GSR-ET.ResultsThe registry was established in June 2015. By 31 December 2017, 1662 patients were enrolled in 23 active sites. Mean age was 72 ± 13 years, 50% were female, and median National Institutes of Health Stroke Scale on admission was 15 (IQR 10-19), 88% had anterior circulation occlusion. Median ASPECT score was 8 (IQR 7-10) prior to intervention. Fifty-nine percent of patients received intravenous thrombolysis prior to thrombectomy. Mean "onset-to-groin" time was 224 ± 176 min.ConclusionsBaseline characteristics of stroke patients undergoing thrombectomy in clinical practice differ from those in the randomized trials. The GSR-ET will provide valuable insights into practices of endovascular treatment in routine care of acute ischemic stroke. (GSR-ET ClinicalTrials.gov Identifier: NCT03356392.).

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