• African health sciences · Sep 2014

    Review

    Basis of selection of first and second line highly active antiretroviral therapy for HIV/AIDS on genetic barrier to resistance: a literature review.

    • Christine Katusiime, Ponsiano Ocama, and Andrew Kambugu.
    • Makerere University, College of Health Sciences, Infectious Diseases Institute, Kampala, Uganda.
    • Afr Health Sci. 2014 Sep 1; 14 (3): 679-81.

    AbstractThe effectiveness of combination antiretroviral therapy (cART) continues to improve as treatment choices expand with the development of new antiretroviral agents and regimens. However, the successful long-term treatment of HIV/AIDS is under threat from the emergence of drug-resistant strains to multiple agents and entire drug classes.

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