• Cleve Clin J Med · Apr 2013

    Review

    Carbapenem-resistant Enterobacteriaceae: a menace to our most vulnerable patients.

    • Federico Perez and David Van Duin.
    • Research Service, Louis Stokes Cleveland Department, of Veterans Affairs Medical Center, Cleveland, OH, USA.
    • Cleve Clin J Med. 2013 Apr 1; 80 (4): 225-33.

    AbstractThe emergence of carbapenem-resistant Enterobacteriaceae (CRE) highlights the importance of effective antibiotics to maintain the safety of our health care system. Clinicians will encounter CRE as a cause of difficult-to-treat and often fatal infections in hospitalized patients. We review the mechanisms of carbapenem resistance, the dissemination and clinical impact of these resistant organisms, and challenges to their detection, treatment, and control.

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