• Feng Zhu and Bo Zhang.
• Feng Zhu, Attending Doctor Department of Respiratory and Critical Care Medicine, The Second Clinical Medical College, Yangtze University, Jingzhou Central Hospital, Jingzhou 434000, China.
• Pak J Med Sci. 2021 Jan 1; 37 (6): 1705-1709.

ObjectiveWe used U-shaped convolutional neural network (U_Net) multi-constraint image segmentation method to compare the diagnosis and imaging characteristics of tuberculosis and tuberculosis with lung cancer patients with Computed Tomography (CT).MethodsWe selected 160 patients with tuberculosis from the severity scoring (SVR) task is provided by ImageCLEF Tuberculosis 2019. According to the type of diagnosed disease, they were divided into tuberculosis combined with lung cancer group and others group, all patients were given chest CT scan, and the clinical manifestations, CT characteristics, and initial suspected diagnosis and missed diagnosis of different tumor diameters were observed and compared between the two groups. The research continued for a year in the office, mainly relying on a computer with GPU to carry out graphics analysis.ResultsThere were more patients with hemoptysis and hoarseness in pulmonary tuberculosis combined with lung cancer group than in the pulmonary others group (P<0.05), and the other symptoms were not significantly different (P>0.05). Tuberculosis combined with lung cancer group had fewer signs of calcification, streak shadow, speckle shadow, and cavitation than others group; however, tuberculosis combined with lung cancer group had more patients with mass shadow, lobular sign, spines sign, burr sign and vacuole sign than others group.ConclusionThe symptoms of hemoptysis and hoarseness in pulmonary tuberculosis patients need to consider whether the disease has progressed and the possibility of lung cancer lesions. CT imaging of pulmonary tuberculosis patients with lung cancer usually shows mass shadows, lobular signs, spines signs, burr signs, and vacuoles signs. It can be used as the basis for its diagnosis. Simultaneously, the U-Net-based segmentation method can effectively segment the lung parenchymal region, and the algorithm is better than traditional algorithms.Copyright: © Pakistan Journal of Medical Sciences.

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