• Curēus · Sep 2021

    Case Reports

    A Rare Variant of Guillain-Barre Syndrome Following Ad26.COV2.S Vaccination.

    • Zachary P Morehouse, Amanda Paulus, Sri A Jasti, and Xue Bing.
    • Family and Community Medicine, Michigan State University College of Osteopathic Medicine, East Lansing, USA.
    • Cureus. 2021 Sep 1; 13 (9): e18153.

    AbstractEfforts to combat the global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) range from adequate diagnostic testing and contract tracing to vaccination for the prevention of coronavirus disease 2019 (COVID-19). In the United States alone, three vaccinations have been authorized for emergency use (EUA) or approved to prevent COVID-19. The Ad26.COV2.S vaccine by Johnson and Johnson (New Brunswick, New Jersey) is the only adenovirus-based vaccine and deemed relatively effective and safe by the US Food and Drug Administration (FDA) following its clinical trial. Since its introduction, the US FDA has placed a warning on the vaccine adverse event reporting system (VAERS) after more than 100 cases of Guillain-Barre Syndrome (GBS) were reported. Herein, we outline the hospital course of a generally healthy 49-year-old female who experienced an axonal form of GBS nine days after receiving the Ad26.COV2.S vaccine.Copyright © 2021, Morehouse et al.

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