• Der Schmerz · Aug 2003

    [Laxative use and efficacy in palliative care of patients with cancer pain and morphine therapy. A retrospective study with special regard to polyethylene glycol].

    • S Wirz and E Klaschik.
    • Klinik und Poliklinik für Anästhesiologie und spezielle Intensivmedizin, Rheinische Friedrich-Wilhelms-Universität Bonn. s.wirz@web.de
    • Schmerz. 2003 Aug 1; 17 (4): 233-9.

    GoalGoal of this study was the assessment of the frequency of constipation in patients of palliative care medicine and the efficacy of the use of laxatives.MethodsIn a retrospective study the computerized data of 206 patients were analysed by descriptive statistics.ResultsConstipation occurred in 42.7% of patients. Constipation appeared in 34% of 159 patients, who were treated with morphine. There was no correlation to gastrointestinal tumors. Laxatives were given to 74.3% of patients. Laxative use was uncomplicated in 78.4%. For therapy of constipation combined administration of polyethylene glycol, sodium picosulphate and paraffin was most effective.ConclusionIn palliative care patients the use of polyethylene glycol is recommended for treating morphine-related-constipation.

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