• H Henkes, S R Felber, K U Wentz, F Czerwinski, H Monstadt, W Weber, and D Kühne.
• Department of Radiology and Neuroradiology, Alfried Krupp Krankenhaus, Essen, Germany.
• Br J Radiol. 1999 May 1; 72 (857): 448-51.

AbstractIntravascular pressure measurements are considered useful for the monitoring and assessment of endovascular treatment effects in intracranial vascular malformations. Experimental data on the accuracy of these measurements are limited. A flow phantom with defined intraluminal pressures and pulsatility flow waveforms was used in this study. Microcatheters commercially available for neuroendovascular procedures (length 140-155 cm), with different outer (0.5-0.83 mm) and inner (0.3-0.53 mm) diameters, were introduced into the phantom in the direction of flow. In a static experiment, pressure values from 0 to 75 mmHg were applied, and in the dynamic part of the experiment mean pressure values from 25 to 65 mmHg, with a pulsatile amplitude from 70 to 170 mmHg were employed. In the static experiment, there was a linear relationship between the pressure values obtained through the microcatheters and the local transducer of the flow phantom. The pulsatile experiments showed increased damping of the pressure waveforms with decreasing inner diameter of the microcatheters. However, the mean pressure values remained accurate. This experimental study has shown that mean pressure values can be accurately measured through microcatheters from 0.3-0.5 mm inner diameter and more than 140 cm in length. In vivo pressure measurements during interventional procedures are therefore reproducible and can be used for monitoring of embolization effects in patients.

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