• Amudalat Issa, Mohammed Baba Abdulkadir, Omotayo Olukemi Adesiyun, Bilkis Owolabi, Habibat Suberu, Kayode Olusegun Alabi, and Ruqayat Ronke Bakare.
• Children Specialist hospital, Ilorin, Nigeria.
• Afr Health Sci. 2021 Jun 1; 21 (2): 743-752.

BackgroundPerinatal asphyxia is a condition associated with multiple organ dysfunctions inclusive of cardiovascular dysfunction. Neurologic predictors of survival have been studied, but little has been reported regarding cardiovascular signs and their role in determining outcome in asphyxia.ObjectiveThe study aimed to determine the relationship between cardiovascular signs and outcomes in asphyxiated newborns with hypoxic ischaemic encephalopathy.MethodsThis was a cross sectional study involving asphyxiated new-born babies recruited within the first 24 hours of life. Hypoxic ischaemic encephalopathy staging was done using Sarnat and Sarnat staging. All patients had a detailed cardiovascular examination on admission, after initial resuscitation (30 - 60 minutes) into admission, and were followed till final outcome: discharge or death.ResultsEighty-five asphyxiated new-borns with HIE were studied over seven months. Abnormal cardiovascular-related signs identified in the patients included respiratory distress (64.7%), small volume pulse (57.6%), hypotension (52.9%), hypoxemia (48.2%) and shock (32.9%). Five babies died. None of the clinical signs had a significant relationship with mortality.ConclusionAbnormal cardiovascular signs increased with the progression of HIE staging but had no relationship with mortality.© 2021 Issa A et al.

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