• Arch Med Sci · Jan 2021

    Follicular and serum levels of vitamin D in women with unexplained infertility and their relationship with in vitro fertilization outcome: an observational pilot study.

    • Ana Jeremic, Zeljko Mikovic, Ivan Soldatovic, Emina Sudar-Milovanovic, Esma R Isenovic, and Milan Perovic.
    • Clinic for Gynaecology and Obstetrics, "Narodni front", Belgrade, Serbia.
    • Arch Med Sci. 2021 Jan 1; 17 (5): 1418-1422.

    IntroductionFollicular and serum vitamin D are considered potential markers of the oocyte and embryos' quality and predictors of in vitro fertilization (IVF) outcomes.MethodsThis retrospective cross-sectional study correlated vitamin D in sera and follicular fluid of women with unexplained infertility mutually and with IVF outcomes. ELISA was used for measuring vitamin D.ResultsThe results show positive correlation only between follicular and serum levels of vitamin D (Rho = 0.615, p = 0.025), and between follicular levels of vitamin D and the percentage of embryo fragmentation (Rho = 0.544; p = 0.036).ConclusionsThe results suggest that serum and follicular fluid vitamin D measurements could be complementary tools to the routine assessment of embryos.Copyright: © 2021 Termedia & Banach.

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