• Fundam Clin Pharmacol · Apr 2010

    Review

    Adaptive designs for Phase I dose-finding studies.

    • Yinghui Zhou.
    • The University of Reading, Berkshire, UK. y.zhou@reading.ac.uk <y.zhou@reading.ac.uk>
    • Fundam Clin Pharmacol. 2010 Apr 1; 24 (2): 129-38.

    AbstractImproving methodology for Phase I dose-finding studies is currently of great interest in pharmaceutical and medical research. This article discusses the current atmosphere and attitude towards adaptive designs and focuses on the influence of Bayesian approaches.

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