• Leonard A Kaminsky, Ross Arena, Jonathan Myers, James E Peterman, Amanda R Bonikowske, Matthew P Harber, Jose R Medina Inojosa, Carl J Lavie, and Ray W Squires.
• Fisher Institute for Health and Well-Being, College of Health, Ball State University, Muncie, IN, USA; Clinical Exercise Physiology Laboratory, College of Health, Ball State University, Muncie, IN, USA; Healthy Living for Pandemic Event Protection (HL - PIVOT) Network, Chicago, IL, USA. Electronic address: kaminskyla@bsu.edu.
• Mayo Clin. Proc. 2022 Feb 1; 97 (2): 285-293.

ObjectiveTo provide updated reference standards for cardiorespiratory fitness (CRF) for the United States derived from cardiopulmonary exercise (CPX) testing when using a treadmill or cycle ergometer.Patients And MethodsThirty-four laboratories in the United States contributed data to the Fitness Registry and the Importance of Exercise National Database. Analysis included 22,379 tests (16,278 treadmill and 6101 cycle ergometer) conducted between January 1, 1968, through March 31, 2021, from apparently healthy adults (aged 20 to 89 years). Percentiles of peak oxygen consumption for men and women were determined for each decade from 20 through 89 years of age for treadmill and cycle exercise modes, as well as when defining maximal effort as respiratory exchange ratio (RER) greater than or equal to 1.0 or RER greater than or equal to 1.1.ResultsFor both men and women, the 50th percentile scores for each exercise mode decreased with age and were higher in men across all age groups and higher for treadmill compared with cycle CPX. The average rate of decline per decade over a 6-decade period was 13.5%, 4.0 mLO2·kg-1·min-1 for treadmill CPX and 16.4%, 4.3 mLO2·kg-1·min-1 for cycle CPX. Observationally, the mean peak oxygen consumption was similar whether using an RER criterion of greater than or equal to 1.0 or greater than or equal to 1.1 across the different test modes, ages, and for both sexes. The updated reference standards for treadmill CPX were 1.5 - 4.6 mLO2·kg-1·min-1 lower compared with the previous 2015 standards whereas the updated cycling standards were generally comparable to the original 2017 standards.ConclusionThese updated cardiorespiratory fitness reference standards improve the representativeness of the US population compared with the original standards.Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

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