• Moayed N Alkhlewi, Hasan M Al-Dorzi, Farhan Z Alenezi, Abdulrahman M Farhat, Hani Tamim, Musharaf Sadat, Felwa Bin Humaid, and Yaseen M Arabi.
• From the Department of Emergency Medicine and Critical Care (Alkhlewi); from the Intensive Care Department (Al-Dorzi, Alanazi, Sadat, Bin Humaid, Arabi), King Abdulaziz Medical City, and from the Ministry of National Guard-Health Affairs; from the College of Medicine (Alkhlewi, Al-Dorzi, Alanazi, Sadat, Tamim, Arabi), King Saud bin Abdulaziz University for Health Sciences; from King Abdullah International Medical Research Center (Alkhlewi, Al-Dorzi, Alanazi, Farhat, Tamim, Sadat, Humaid, Arabi), Riyadh; from the Faculty of Medicine (Farhat), Sulaiman Alrajhi University, Qassim, Kingdom of Saudi Arabia; and from the Department of Internal Medicine (Tamim), American University of Beirut, Beirut, Lebanon.
• Saudi Med J. 2021 Dec 1; 42 (12): 1320-1324.

ObjectivesTo evaluate the outcomes of cirrhotic patients admitted to the intensive care unit (ICU) following cardiac arrest.MethodsThis was a single centre retrospective study of all the cirrhotic patients, admitted to the ICU at King Abdulaziz Medical City, Riyadh, Saudi Arabia, after a successful cardiac arrest resuscitation, from 1999 to 2017. The characteristics of the hospital survivors and non-survivors were compared.ResultsA total of 76 patients were admitted to the ICU during the study period, with a median age of 64 years. In addition to cirrhosis, the patients had other chronic comorbidities, including chronic renal disease (32.9%) and diabetes (47%). Of this group, 67 (88.2%) died in the hospital, and 54 (71%) died while in ICU. Compared to the group who survived, all non-survivors required mechanical ventilation and had a higher median APACHE II score of 38 (p=0.006), a lower median Glasgow coma score (GCS) of 3 (p=0.0003), and a higher median lactic acid of 6.4 mmol/L (p=0.032). On multivariable logistic regression analysis, the important predictors of hospital mortality were APACHE II score (p=0.006), bilirubin level (p=0.008) and GCS (p=0.005).ConclusionCirrhotic patients admitted to the ICU following cardiac arrest have high mortality. Patients with higher APACHE II scores, higher bilirubin and lower GCS have higher risk of in-hospital mortality.Copyright: © Saudi Medical Journal.

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