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- B Zhang, X Yu, H Mao, C Xing, and J Liu.
- Department of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
- W Indian Med J. 2013 Jan 1; 62 (1): 92-4.
AbstractWe report a case of a 76-year old female presenting with symptomatic severe hypercalcaemia, and subsequently diagnosed with late onset SLE due to the presence of anaemia, leucopenia, antibodies of antinuclear (ANA), anti-dsDNA, and also kidney impairment. Serum levels of FGF23 and intact-parathyroid hormone (iPTH) were low in this patient. Serum calcium, FGF23 and iPTH levels responded to steroids, which occurred simultaneously with disease activity. On follow-up, the faster increase in FGF23 than in parathyroid hormone suggested that FGF23 might be involved in the pathogenesis of hypercalcaemia in SLE.
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