• Loretta T Lee, Anne W Alexandrov, Virginia J Howard, Edmond K Kabagambe, Mary A Hess, Rhonda M McLain, Monika M Safford, and George Howard.
• UAB School of Nursing, The University of Alabama at Birmingham, 1720 2nd Ave South, Birmingham, AL 35294-1210, USA. Electronic address: llee@uab.edu.
• Prev Med. 2014 Jun 1; 63: 43-7.

ObjectiveTo determine the association between race, region and pre-diabetes.MethodThe study used 2003-2007 United States baseline data from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study for this cross-sectional analysis. Participants in this study were 45years or older at recruitment. Logistic regression was used to assess whether race and region are associated with pre-diabetes independent of demographics, socioeconomic factors and risk factors.ResultsTwenty-four percent of the study participants (n=19,889) had pre-diabetes. The odds ratio (95% confidence interval) for having pre-diabetes was 1.28 (1.19-1.36) for blacks relative to whites and 1.18 (1.10-1.26) for people living in the Stroke Belt region relative to the other parts of the United States. The odds of having pre-diabetes for Stroke Belt participants changed minimally after additional adjustment for race (OR=1.20; 1.13-1.28), age and sex (OR=1.24; 1.16-1.32), socioeconomic status (OR=1.22; 1.15-1.31) and risk factors (OR=1.26; 1.17-1.35). In the adjusted model, being black was independently associated with pre-diabetes (OR=1.19; 1.10-1.28).ConclusionThe prevalence of pre-diabetes was higher for both blacks and whites living in the Stroke Belt relative to living outside the Stroke Belt, and the prevalence of pre-diabetes was higher for blacks independent of region.Copyright © 2014 Elsevier Inc. All rights reserved.

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