• Internal medicine · Jan 2015

    Hyperglycemia-associated Hemichorea-hemiballism: The Spectrum of Clinical Presentation.

    • Pc Lee, Pc Kek, and Awe Soh.
    • Department of Endocrinology, Singapore General Hospital, Singapore.
    • Intern. Med. 2015 Jan 1; 54 (15): 1881-4.

    AbstractHyperglycemia rarely manifests as hemichorea-hemiballism (HH), which is characterized by simple partial motor seizures. One of the difficulties in the management of hyperglycemia-induced HH is the failure to recognize this entity due to its relatively uncommon presentation. We herein present a case series of hyperglycemia-associated dyskinesias, highlighting the different possible clinical presentations of this entity. Both hyperglycemia and hyperosmolality are probable predisposing factors, while ketoacidosis has a protective role in preventing the dyskinesias. One of our patients had ketotic hyperglycemia leading to HH, a previously unreported finding. Early recognition of this entity is crucial as prompt glycemic control leads to the resolution of symptoms and signs.

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