• Medicine · Jan 2022

    Case Reports

    Klebsiella pneumoniae-related brain abscess and meningitis in adults: Case report.

    • Jingru Zhao, Tiantian Huo, Xintong Luo, Fan Lu, Shuo Hui, and Baoming Yang.
    • Department of Neurology, Hebei General Hospital, 348th Heping West Road, Shijiazhuang, P.R. China.
    • Medicine (Baltimore). 2022 Jan 14; 101 (2): e28415e28415.

    IntroductionKlebsiella pneumoniae is once thought to be a less common cause of brain abscess in adults and is mainly hospital-acquired. Community-acquired CNS infection (brain abscess and meningitis) caused by K pneumoniae without other metastatic septic abscesses is exceedingly rare. Therefore, we present a rare adult patient with invasive cerebral abscess and meningitis without other invasive abscesses related to K pneumoniae.Patient ConcernsA 64-year-old woman experienced a sudden onset of severe continuous headache accompanied by intermittent nausea, vomiting, and fever. Meanwhile, she experienced tinnitus and had a feeling of swelling in the right ear.DiagnosisCranial magnetic resonance imaging revealed abnormal hyperintensity signals in the left head of the caudate nucleus. The next generation sequencing of cerebral spinal fluid showed infection with K pneumoniae. The patient was diagnosed with K pneumoniae-related brain abscesses and meningitis.InterventionsAntibacterial treatment was carried out for 2 months.OutcomesThe patient recovered well.ConclusionDespite the progress of modern neurosurgical techniques, new antibiotics, and modern imaging techniques, brain abscesses are still a potentially fatal infection. Streptococci are common organisms that result in brain abscesses. Nevertheless, Klebsiella species, once thought to be a less common cause of brain abscess in adults, has become an increasingly important cause of brain abscess, especially in Asia.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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