• Saudi Med J · Jan 2022

    Case Reports

    A limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine.

    • Fahdah Alokaily, Reem AlKathiri, Sarah AlKathiri, and Seham Alrashidi.
    • From the Division of Rheumatology (Alokaily, Alrashidi), Department of Medicine; from the Department of Psychiatry (AlKathiri R), Prince Sultan Military Medical City, from the College of Medicine (AlKathiri S), King Saud University, Riyadh, Kingdom of Saudi Arabia.
    • Saudi Med J. 2022 Jan 1; 43 (1): 105-107.

    AbstractThis is a case report of a 31-year-old lady who is known to have ulcerative colitis for 15 years and was on mesalazine. She presented with periorbital swelling, sinusitis, epistaxis, and was found to have positive anti-neutrophil cytoplasmic antibody and anti-proteinase-3 of a high titer. Biopsy from the maxillary sinus showed chronic non-specific inflammation and biopsy from the periorbital fat revealed inflammation and granulomatous changes. She had no other organ involvement. She was diagnosed with a limited form of granumatosis and polyangiitis and treated with methotrexate and prednisolone. The symptoms disappeared after treatment.Copyright: © Saudi Medical Journal.

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