• María Pilar Espejo-Reina, Miriam Prieto-Moreno, Marina De-Miguel-Blanc, Daniela María Pérez-Martínez, Jesús Salvador Jiménez-López, and Susana Monís-Rodríguez.
• Department of Obstetrics and Gynaecology, Regional University Hospital, 29011 Malaga, Spain.
• Medicina (Kaunas). 2022 Jan 10; 58 (1).

AbstractBackground: Aggressive angiomyxoma is a rare entity within mesenchymal cell neoplasms, especially in pregnant women. Its main characteristic is the ability to infiltrate neighboring structures and to recur. Case Presentation: We present the case of a pregnant woman who debuted with a genital prolapse in the second trimester of pregnancy. She was diagnosed with bilateral ovarian teratomas and a pelvic mass of which the diagnosis could not be established until delivery. The route of delivery used was cesarean section since the genital prolapse behaved as a previous tumor. After the puerperium, the patient was referred for consultation to complete the study of the mass. The extension study was carried out with a negative result. The patient underwent surgery for tumor exeresis. Hormonal treatment was not administered according to the patient's preferences. Conclusions: Aggressive angiomyxoma is a benign neoplasm that should be considered in the differential diagnosis of pelvic tumors in women. In pregnant women, the vaginal route of delivery is not contraindicated as long as the tumor does not obstruct the birth canal. The definitive treatment is surgery, preferably performed in a second stage after delivery.

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