• Botao Duan, Xuekai Zhao, Songsong Fan, Lei Zhou, and Xingyuan Zhang.
• Department of Hepatobiliary Surgery, Binzhou Medical University Hospital, Binzhou, China.
• Medicine (Baltimore). 2022 Jan 21; 101 (3): e28478e28478.

RationaleCholangiocarcinoma is a common cause of obstructive jaundice but is mainly associated with solid mass and not semisolid secretion. In this report, the patient was admitted to the hospital with obstructive jaundice; however, no solid mass was found to lead to jaundice.Patient ConcernsThe patient developed symptoms of obstructive jaundice for 10 days, including fatigue and yellow skin staining.DiagnosesPostoperative pathological examination of the bile duct wall revealed cholangioadenocarcinoma, and the jelly like contents were inflammatory secretions.InterventionsThe patient underwent laparotomy and was diagnosed with obstructive jaundice. An exploratory laparotomy revealed that the content in the biliary duct tree was a jelly like inflammatory secretion.OutcomesFollow-up data revealed that the levels of total bilirubin and aminotransferase were normal, and a computed tomography scan showed no tumor mass.LessonsThere are very few reports about obstructive jaundice caused by inflammatory secretion that almost filled up the biliary tree. Internal drainage of the cholestatic bile can be achieved through endoscopic retrograde cholangiopancreatograpy, or external drainage can be achieved through percutaneous transhepatic biliary drainage, which can relieve the symptoms of biliary obstruction and improve the patient's quality of life.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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