• Jesús K Yamamoto-Furusho, Norma N Parra-Holguín, Fabián Juliao-Baños, Fabián Puentes, Rocio López, Francisco Bosques-Padilla, Esther A Torres, Humberto Nieves-Jimenéz, Guillermo R Veitia-Velásquez, Maria L Jara-Alba, Sócrates Bautista, Felipe N Piñol-Jimenez, Pablo Salgado-Rosado, Keyla C Villa-Ovalles, Yudelka A Abreu-Martinez, Zunilda Borges, Santiago Davila-Bedoya, Guillermo Otoya-Moreno, Beatriz Iadé-Vergara, and EPILATAM study group .
• Inflammatory Bowel Disease Clinic, Gastroenterology Department, National Institute of Medical Science and Nutrition Salvador Zubirán, Mexico City, Mexico.
• Medicine (Baltimore). 2022 Jan 21; 101 (3): e28624e28624.

AbstractThe aim of the present study was to describe the epidemiological and clinical characteristics of inflammatory bowel disease (IBD), including medical and surgical treatments, in several countries in Latin America and the Caribbean.IBD is recognized as a global health problem because its incidence and prevalence have increased significantly over the last few years.This multicenter retrospective cohort study included 4714 patients with IBD diagnosed from 9 countries in Latin America and the Caribbean: Colombia, Cuba, Dominican Republic, Ecuador, Mexico, Peru, Puerto Rico, Uruguay, and Venezuela.Crohn disease (CD) was more frequent in Puerto Rico (71.9%), the Dominican Republic (61.0%), and Peru (53.1%). Ulcerative colitis was more frequent in Colombia (78.6%), Venezuela (78.2%), Mexico (75.5%), Cuba (69.9%), Ecuador (64.1%), and Uruguay (60.9%). The following clinical characteristics were more frequent in the Caribbean: penetrating behavior in CD, steroid dependence, steroid resistance, intolerance to thiopurines, extraintestinal manifestations, surgeries, hospitalizations due to IBD, and family history of IBD. The factors associated with the use of biological therapy were pancolitis in ulcerative colitis, penetrating behavior in CD, steroid resistance and dependence, presence of extraintestinal manifestations, and the need for surgery.This study from Latin America and the Caribbean demonstrated the different epidemiological and clinical characteristics of IBD.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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