• Hongshuo Shi, Cengda Dong, Wenbin Liu, Min Peng, Guomin Si, and Fengshan Sun.
• College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.
• Medicine (Baltimore). 2022 Jan 28; 101 (4): e28707e28707.

BackgroundPoststroke depression (PSD) is a syndrome that occurs after stroke. The efficacy of Chinese herbal medicine (CHM) for PSD has also received widespread attention, but there is still a lack of clinical evidence because this overview evaluates the published meta-analyses (MAs)/Systematic reviews (SRs). To provide evidence for the clinical application of CHM in the treatment of PSD.MethodsTwo researchers searched 7 databases for SRs/MAs which are about randomized controlled trials on CHM for PSD. Two investigators use the systematic review assessment tool (AMSTAR-2), the risk of bias in systematic scale, the list of preferred reporting items for systematic reviews and meta-analysis, and the classification of recommended assessments for evaluation, development and evaluation system to assess the included SRs/MAs.ResultsOur findings will be published in peer-reviewed journals.ConclusionThis study provides evidence-based medical evidence for the impact of CHM on PSD.Registration NumberINPLASY202210001.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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