• Chuan Zhong, Fen Wang, Haining Zhou, Jiarui Liu, Jiewei Hu, and Yongjun Chen.
• Department of Thoracic Surgery, Suining Central Hospital, Suining, Sichuan, China.
• Medicine (Baltimore). 2022 Jan 28; 101 (4): e28719e28719.

RationaleBacillus licheniformis (B licheniformis) is a commonly used microbiota modulator. However, infections are rarely observed in immunocompetent hosts.Patient ConcernsA 67-year-old woman who underwent esophagectomy experienced accidental injection of B licheniformis and presented with chills followed by hyperpyrexia.DiagnosisThe initial diagnosis was B licheniformis bacteremia.InterventionBased on our experience, the patient first received levofloxacin and ornidazole. The application of levofloxacin was retained based on the antibiogram results. After discharge, the antibiotics were changed to vancomycin and levofloxacin, based on sensitivity tests, until two consecutive blood cultures were negative.OutcomesThe patient recovered without any severe complications.LessonsThis is a rare report of the successful treatment of B licheniformis bacteremia caused by improper drug administration, which will provide a reference for the treatment of B licheniformis bacteremia.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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