• Preventive medicine · Mar 2012

    Longitudinal changes in weight in relation to smoking cessation in participants of the EPIC-PANACEA study.

    • Noémie Travier, Antonio Agudo, Anne M May, Carlos Gonzalez, Jian'an Luan, Nick J Wareham, H Bas Bueno-de-Mesquita, Saskia W van den Berg, Nadia Slimani, Sabina Rinaldi, Françoise Clavel-Chapelon, Marie-Christine Boutron-Ruault, Domenico Palli, Sabina Sieri, Amalia Mattiello, Rosario Tumino, Paolo Vineis, Teresa Norat, Dora Romaguera, Laudina Rodriguez, Maria-José Sanchez, Miren Dorronsoro, Aurelio Barricarte, José M Huerta, Tim J Key, Philippos Orfanos, Androniki Naska, Antonia Trichopoulou, Sabina Rohrmann, Rudolf Kaaks, Manuela M Bergmann, Heiner Boeing, Goran Hallmans, Ingegerd Johansson, Jonas Manjer, Björn Lindkvist, Mariane U Jakobsen, Kim Overvad, Anne Tjonneland, Jytte Halkjaer, Eiliv Lund, Toni Braaten, Andreani Odysseos, Elio Riboli, and Petra H Peeters.
    • Unit of Nutrition, Environment and Cancer, Catalan Institute of Oncology, IDIBELL, Barcelona, Spain. ntravier@iconcologia.net
    • Prev Med. 2012 Mar 1; 54 (3-4): 183-92.

    PurposeWe assessed the association between smoking cessation and prospective weight change in the European population of the European Prospective Investigation into Cancer and Nutrition-Physical Activity, Nutrition, Alcohol, Cessation of smoking, Eating out of home And obesity (EPIC-PANACEA) project.MethodsThe study involved more than 300,000 healthy volunteers, recruited between 1992 and 2000 in 9 European countries, who provided data on anthropometry and smoking habits at baseline and after a follow-up of 5 years on average. Adjusted mixed-effects linear regression models were used to obtain sex-specific summary estimates of the association between the change in smoking status and the annual change in weight.ResultsSmoking cessation tends to be followed by weight gain; when compared to stable smokers, annual weight gain was higher in men (0.44 kg (95%CI: 0.36; 0.52)) and women (0.46 kg (95%CI: 0.41; 0.52)) who stopped smoking during follow-up. When smokers who stopped smoking at least 1 year before recruitment were compared to never smokers, no major differences in annual weight gain were observed. The excess weight gain following smoking cessation appears to mainly occur in the first years following the cessation.ConclusionsWhen considering the benefits of smoking cessation, such findings strengthen the need for promoting cessation offering information on weight gain control and support to weight-concerned smokers in order to remove a barrier to quitting.Copyright © 2011 Elsevier Inc. All rights reserved.

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