• Murat Demir, Kasim Ertas, Rahmi Aslan, Recep Eryilmaz, Mehmet Sevim, and Kerem Taken.
• Department of Urology, Faculty of Medicine, Van Yuzuncu Yil University, Van, Turkey.
• J Coll Physicians Surg Pak. 2022 Feb 1; 32 (2): 197-201.

ObjectiveTo investigate the effect of preoperative tamsulosin use on the success and complications rates of ureteroscopy for ureteral stone removal.Study DesignA randomised clinical trial.Place And Duration Of StudyDepartment of Urology, Dursun Odabas Medical Center, Van Yuzuncu Yil University, Turkey, from December 2020 to June 2021.MethodologyPatients were scheduled for ureteroscopy due to ureteral stones, and were randomly divided into two groups; 67 patients preoperatively were given 0.4 mg tamsulosin for 7 days and 70 patients were not given tamsulosin. Each patient's intraoperative surgical complications, preoperative and postoperative pain, postoperative fever, need for analgesia, stone-free rate, and double J ureteral stent (DJ) insertion rates were recorded and evaluated.ResultsA total of 137 patients, 103 (75.1%) males, and 34 (24.8%) females, were included. In 70 (51.1%) of these patients, the stone was on the right side, while in 67 (48.9%) the stone was on the left side. The stone was in the distal ureter in 47 (34.3%) patients, in the middle in 38 (27.7%) patients, and the proximal in 52 (37.9%) patients. The patients who were given tamsulosin had lower preoperative visual analog scale (p=0.02), operation time (p=0.003), post-ureteroscopic lesion scale (p=0.01), postoperative 24th-hour visual analog scale (p=0.03), fever (p=0.02), and analgesic need (p=0.04), while their rate of accessing the stone (p=0.02); and their stone-free rates (p=0.02) was higher.ConclusionPreoperative tamsulosin use increases the success of the operation and reduces complications. Key Words: Tamsulosin, Ureteral calculi, Ureteroscopy.

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