• Gac Med Mex · Jan 2021

    Relationship of vitamin D blood concentration with muscle mass and cognitive function in postmenopausal women.

    • Sebastián Carranza-Lira, Melissa López-Chávez, Alejandra Díaz-de León-de Luna, Sergio Rosales-Ortiz, and Guadalupe J Méndez-González.
    • Health Research Division.
    • Gac Med Mex. 2021 Jan 1; 157 (5): 484-493.

    IntroductionLow levels of vitamin D have been associated with muscle mass loss and cognitive function alteration.ObjectiveTo find out the relationship of vitamin D blood levels with muscle mass and cognitive function in postmenopausal women.Materials And MethodsNinety-nine postmenopausal women aged ≥ 50 years were studied. Calf circumference, and tricipital, bicipital, subscapular and suprailiac skinfolds were measured. Arm muscle area, bone-free arm muscle area, and muscle mass were calculated. The short physical performance battery (SPPB) was performed, and the sarcopenia rapid diagnostic questionnaire (SARC-F), as well as the Mini Mental State Examination (MMSE) were applied. A blood sample was taken to measure vitamin D blood concentration. For statistical analysis, Mann-Whitney's U-test and Spearman's correlation analysis were used.ResultsIt was found that, the older the age, the higher the vitamin D levels, as well as higher SARC-F score. Vitamin D levels were negatively correlated with grip strength and SPPB. There was a negative correlation between vitamin D levels and MMSE global score.ConclusionsVitamin D did not have a positive influence on muscle mass. A better MMSE performance was observed in those with lower vitamin D levels.Copyright: © 2021 Permanyer.

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