• Erick M Toro-Monjaraz, Karen Ignorosa-Arellano, Karen Raya-Aguirre, Alejandro Loredo-Mayer, Roberto Cervantes-Bustamante, Flora Zárate-Mondragón, José Cadena-León, and Jaime Ramírez-Mayans.
• Department of Gastroenterology and Pediatric Nutrition, Instituto Nacional de Pediatría, Mexico City, Mexico.
• Gac Med Mex. 2021 Jan 1; 157 (5): 473-477.

IntroductionDyspepsia comprises a group of symptoms that can have organic or functional origin. The purpose of this study was to describe the main causes of dyspepsia and its clinical evolution in children cared for in a tertiary care hospital.Material And MethodsRetrospective study in children with dyspepsia. Patients underwent endoscopy with biopsy and rapid urease test to detect the presence of Helicobacter pylori. In case of normal endoscopy and biopsy, hydrogen breath test was performed. In all cases, follow-up was provided in order to evaluate symptom improvement.ResultsOne hundred children were included, out of whom 52 were girls; mean age was 8.59 years. Esophagitis or erosive gastropathy were found in 54% of the cases (n = 54), H. pylori infection in 12% (n = 12), small intestinal bacterial overgrowth in 12% (n = 12), and functional dyspepsia in 20% (n = 20).ConclusionIn children with dyspepsia, organic causes should first be ruled out before dyspepsia being characterized as functional. In general terms, we consider that a stepped approach that includes endoscopy with biopsy, search for H. pylori and hydrogen breath test is necessary.Copyright: © 2021 Permanyer.

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