• Presse Med · Jan 2000

    Review

    [Effect of pregnancy, menopause and hormone substitution therapy on disseminated systemic lupus erythematosus].

    • D Le Thi Huong, B Wechsler, and J C Piette.
    • Service de Médecine interne, Groupe Hospitalier Pitié-Salpêtrière, Paris.
    • Presse Med. 2000 Jan 15; 29 (1): 55-60.

    AbstractEXACERBATIONS DURING PREGNANCY: Clinical and experimental data have clearly evidenced the influence of hormones on the course of systemic lupus erythematosus. In prospective studies of pregnant women, an exacerbation is observed in 57% to 60% of the cases. It can be severe in 10% of the cases and occur in the post partum in 7%. For most patients, the exacerbation is moderate and has no unfavorable effect on the outcome of pregnancy. In case of renal involvement, it is difficult to differentiate an intricated HELPP syndrome.

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