• Presse Med · Apr 2001

    [Hypovitaminosis D: a major worldwide public health problem].

    • M H Gannagé-Yared, A Tohmé, and G Halaby.
    • Département d'Endocrinologie, Hôtel-Dieu de France, rue Adib Ishaac, Beyrouth, Liban.
    • Presse Med. 2001 Apr 7; 30 (13): 653-8.

    AbstractPHYSIOLOGY: Vitamin D increases intestinal absorption of calcium favoring the microenvironment necessary for bone mineralization. In addition, vitamin D prevents hypocalcemia via its osteoclastic action. Severe hypovitaminosis leads to rickets in children and its equivalent in adults, osteomalacia. Mild to moderate hypovitaminosis D causes secondary hyperparathyroidism increasing the risk of fracture, particularly femoral neck fracture. Vitamin D would also have an antiinflammatory and anticancer effect.

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