• Fatma Bozkurt, Omer Coskun, and Sevda Yelec.
• Department of Infectious Diseases and Clinical Microbiology, University of Health Science, Gazi Yaşargil Education and Research Hospital, Diyarbakir, Turkey.
• Afr Health Sci. 2021 Dec 1; 21 (4): 1567-1573.

BackgroundIn pregnancy, Coronavirus disease-2019 (COVID-19) infection disease may be more severe due to existing physiological changes. Similarly, changes during and after birth can make the patient more subceptible.ObjectiveTo investigate possible laboratory findings that was related to postpartum progression of COVID-19 disease.MethodsPregnant women who are pregnant at 28 weeks or more and who are COVID-19 positive at the time of delivery were investigated in this study. Progressed post- delivery and non-progressed COVID-19 positive pregnants' laboratory findings were analyzed. Hematological and immunological parameters associated with postpartum progressed COVID-19 disease were evaluated.ResultsTotally 151 individuals were conducted to the study. In the prenatal analysis, higher BMI and lower albumin levels were detected in the progressed group (p<0.05). In the postpartum analysis; White Blood Cell, lymphocyte and albumin were increased, while neutrophil, NLR, LDH, CK, D-DIMER, Ferritin, CRP and IL-6 were decreased in the non-progressed group as opposite of the progressed group (p<005).ConclusionWe observed that prenatal low albumin and high BMI may be related to progression of the COVID-19 disease after delivery. In progressed group, inflammatory markers were increased after delivery while in non-progressed group they were improved. These markers may be warning for the postpartum progression of COVID-19 disease.© 2021 Bozkurt F et al.

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