• Sarah Maria Najjuka, Gaudencia Checkwech, Ronald Olum, Scholastic Ashaba, and Mark Mohan Kaggwa.
• Makerere University, College of Health Sciences, Uganda, P.O. Box 7062, Kampala.
• Afr Health Sci. 2021 Dec 1; 21 (4): 1533-1543.

BackgroundCOVID19 pandemic forced most countries to lockdown, leading to the prolonged closure of many learning institutions. This dramatic shift led to increase of mental illness symptoms among university students.ObjectiveTo determine the prevalence and factors associated with symptoms of depression, anxiety, and stress among Uganda's university students during the COVID-19 lockdown.MethodsWe conducted a one-month online survey using the Depression Anxiety and Stress Scale (DASS-21).ResultsParticipants n=321 were enrolled with mean age, 24.8(SD=5.1) years and 198(61.7%) were males. The prevalence of mental health symptoms among participants was 80.7%, 98.4%, and 77.9% for depression, high levels of anxiety, and stress, respectively. Statistically significant association between mental health symptoms on multi-logistic regression was found with Males (depression=2.97[1.61-5.48] and stress=1.90[1.07-3.35]), engagement in leisure activity (depression= 1.87[1.01-3.49] and stress=1.98[1.10-3.56]), and being finalist (stress=0.55[0.31- 0.97]). Use of addictive substances seem to potentially alleviate symptoms of depression, anxiety and stress in the short term.ConclusionsThe findings of this study suggest a high prevalence of symptoms of depression, anxiety and stress among university students during the COVID-19 lockdown. Students' mental health should be monitored by all stakeholders, especially as the pandemic progresses.© 2021 Najjuka SM et al.

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