• Gökhan Karaşin, Yasemin Bayram, Mehmet Parlak, Cenk Aypak, Mustafa Akgül, and Hüseyin Güdücüoğlu.
• Microbiology Laboratory. Van Training and Research Hospital, 65300, Van, Turkey.
• Afr Health Sci. 2021 Dec 1; 21 (4): 1662-1668.

BackgroundMulti-drug resistant organisms, especially Vancomycin-Resistant Enterococcus (VRE) and Carbapenam Resistant Klebsiella pneumoniae (KPC), are serious health threat. Early detection of resistant bacteria colonization among patients in intensive care units (ICUs) not only enables effective treatment but more importantly prevents disease and limits transmission. Therefore, we aimed to to assess the frequency of VRE and KPC colonization via rectal swab sampling.MethodsThe study was carried out in ICUs of a tertiary hospital. Two rectal swab samples were collected within the first 24 hours of admission and another one was taken every subsequent 15 days to test for for VRE and KPC carriage.ResultsA total 316 rectal swab samples taken from 230 patients. Forty-seven patients were screened at least 2 times. 183 patients were not further screened due to discharge, exitus or transfer to other wards. Thirty-six patients (16%) were determined to be VRE (+). The most frequently isolated strain was E. faecium (80.5%) and its most common genotype was VanA (87.5%). Seven patients (3%) were identified as KPC (+). OXA-48 type crbapenamase was confirmed in all KPC isolates.ConclusionThis study shows that VRE and KPC colonization continues to be a serious threat in ICUs.© 2021 Karaşin G et al.

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