• Postgrad Med J · Jun 2023

    Review

    Development process and clinical application of collagenase chemonucleolysis in the treatment of lumbar disc herniation: a narrative review in China.

    • Peng Yuan, Xiaohua Shi, Xuanjun Wei, Zijun Wang, Jiao Mu, and Hongxin Zhang.
    • Interventional Radiology and Pain Treatment, The Second Affiliated Hospital of Air Force Medical University, Air Force Medical University, Xi'an, China.
    • Postgrad Med J. 2023 Jun 15; 99 (1172): 529534529-534.

    AbstractLumbar disc herniation (LDH) is one of the most common causes of lumbocrural pain. In the past 20 years, the incidence of LDH has increased dramatically. There are many treatments for LDH, including conservative treatment (such as acupuncture and physiotherapy), minimally invasive interventional treatment (such as collagenase chemonucleolysis and radiofrequency ablation) and surgical treatment. The main purpose of this paper is to review the development process and application status of collagenase chemonucleolysis in the treatment of LDH at home and abroad and provide a reference for clinical treatment.© The Author(s) 2022. Published by Oxford University Press on behalf of Postgraduate Medical Journal. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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