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J Coll Physicians Surg Pak · Apr 2016
Short Term Donor Outcomes After Hepatectomy in Living Donor Liver Transplantation.
- Faisal Saud Dar, Haseeb Zia, Hafeez BhattiAbu BakarABDepartment of HPB and Liver Transplantation, Shifa International Hospital, Islamabad., Atif Rana, Rashid Nazer, Rubab Kazmi, Etizaz-Ud-Din Khan, Nasir Ayub Khan, Muhammad Salih, and Najmul Hassan Shah.
- Department of HPB and Liver Transplantation, Shifa International Hospital, Islamabad.
- J Coll Physicians Surg Pak. 2016 Apr 1; 26 (4): 272-6.
ObjectiveTo determine the outcome of living-donor liver transplant (LDLT) donors from the first liver transplant program in Pakistan.Study DesignCohort study.Place And Duration Of StudyShifa International Hospital, Islamabad, from April 2012 to August 2014.MethodologyA total of 100 live donors who underwent hepatectomy were included. Demographics, etiologies, graft characteristics and operative variables were retrospectively assessed. Outcome was assessed based on morbidity and mortality.ResultsMedian donor age was 28 (17 - 45) years and median body mass index (BMI) was 24 kg/m2 (15 - 36). Male to female ratio was 1.5:1. Hepatitis B and C were the most common underlying etiologies and accounted for 79/100 (79%) of LDLT's. Overall, 93/100 (93%) donors donated a right lobe graft. Median estimated graft weight to recipient body weight (GW/BW) ratio was 1.03 (0.78 - 2). Standard arterial anatomy was present in 56% donors. The 90-day morbidity was 13/100 (13%) and overall morbidity was 17/100 (17%). Bile leak was encountered in 3 (3%) patients. There was no donor mortality.ConclusionAcceptable short-term donor outcomes were achieved in an LDLT program in Pakistan with careful donor selection and planning.
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