• Muhammad Imran Hassan Khan, Usama Azhar, Fizza Zubair, and Zohaib Abbas Khan.
• Dr. M. Imran Hasan Khan, MBBS (Pb) MRCP (UK), FCPS (MED), MRCPS (Glas), FRCP (Edin) FRCP (Glas) FRCP (LONDON) Department of Medicine, Ameer-ud-Din Medical College/ PGMI, Lahore General Hospital, Lahore, Pakistan.
• Pak J Med Sci. 2018 Nov 1; 34 (6): 137513801375-1380.

ObjectiveAlthough many studies worldwide explained the risk factors for developing Diabetic Foot Ulceration (DFU), little has been done to assess medical factors in DFU formation and link them in patients of Pakistan. This study aimed to link the DFU with different risk factors.MethodsThis descriptive cross-sectional retrospective study was conducted in Diabetes Endocrine and Metabolic Centre / Post Graduate Medical Institute / Lahore General Hospital. Data of all patients presenting between July 2017 to June 2018 were analyzed for risk factors. Analysis was done on SPSS version 21.ResultsTotal of 3301 patient were seen during this period, out of which 2052 patient data was picked up as it was complete in respect to the information needed. Middle age, Male gender, Type 2 diabetes, and Hypertension, were insignificantly co-related. High waist circumference, Comorbidity like Neuropathy, Dyslipidemia, Greater body mass index, Poor compliance with Medication and type of medication used (combination of oral and injectable) were found statistically significant predictor for DFU. However retinopathy was not found to be a risk factor of DFU. This result was statistically significant.ConclusionFactors like obesity, waist circumference, combination of oral along with injectable therapies, neuropathy, dyslipidemia, retinopathy and poor compliance with medication were statistically significant and can be strongly linked with diabetic foot ulcer. Middle age, Male gender, Type 2 diabetes, and Hypertension were insignificantly co-related. However, further studies are needed in larger population to support these findings.

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