• Shiwen Xi and Weihua Tong.
• Department of Gastric and Colorectal Surgery, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
• Medicine (Baltimore). 2018 Dec 1; 97 (51): e13648e13648.

RationalePleomorphic rhabdomyosarcoma (PRMS) is a rare soft tissue malignancy which is frequently misdiagnosed and associated with metastasis to the lungs, lymph nodes, and bone marrow. Case studies are needed to improve the awareness of the disease and our understanding of it.Patient ConcernsIn this study, we present a case of a 36-year-old man with a lesion on the right back shoulder. Lesion was confirmed by magnetic resonance imaging (MRI) around the right armpit, subscapularis, deltoid, and infraspinatus muscle, with oozing surrounding soft tissues.DiagnosisThe tumor was diagnosed as PRMS which metastasized to the intestine, where it caused intussusception.InterventionsThe patient was treated by complete surgery in combination with neo-adjuvant chemotherapy including ifosfamide and epirubicin.OutcomeThe patient remained alive 6 months after the treatment with no recurrence and metastasis.LessonPRMS can be aggressive, and surgical treatment in combination with multidrug chemotherapy can be used in the management.

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