• Pengfei Jing, Bing Wei, and Xiaoqin Yang.
• Department of General Surgery.
• Medicine (Baltimore). 2018 Dec 1; 97 (52): e13767.

RationalePhyllodes tumors (PTs) of the breast are rare biphasic fibroepithelial neoplasms which usually present with unilateral palpable breast lumps. Here we reported a case of borderline PTs with multifocal intraductal lesions whose primary clinical manifestation was nipple discharge.Patient ConcernsA rare case of PT with nipple discharge in a 26-year-old young lady accepted a wide local excision on her left breast, and the pathological examination turned out to be a malignant phyllodes tumor. After a 12-month follow-up, no local or distant recurrence was observed.DiagnosisBorderline PTs with multifocal intraductal lesions INTERVENTIONS:: The patient received wide local excision with clear margin. After the operation, the patient is undergoing surveillance through ultrasonography and physical examination every 3 months.OutcomesAfter a follow-up of 12 months, no local or distant recurrence was observed.LessonsThe lesions of the PTs are often manifested with unilateral, palpable masses in the breast. There are very few case reports of PTs manifested with nipple discharge in the literature. We should improve the understanding of the multiple clinical manifestations of PTs.

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